Keratinocyte Carcinoma

Exposed hardware in a patient with invasive keratinocyte carcinoma

KC: keratinocyte carcinoma SCC: squamous cell carcinoma INTRODUCTION The care of patients with aggressive keratinocyte carcinomas (KCs), including squamous cell carcinoma (SCC) and basal cell carcinoma, is often multidisciplinary and includes dermatologic surgeons, plastic surgeons, otolaryngologists, and other surgical subspecialties. Complex reconstructions might require osteosynthetic materi...

From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma.

Cutaneous squamous cell carcinoma (cSCC) is the second most common human cancer with over 250,000 new cases annually in the US and is second in incidence only to basal cell carcinoma. cSCC typically manifests as a spectrum of progressively advanced malignancies, ranging from a precursor actinic keratosis (AK) to squamous cell carcinoma (SCC) in situ (SCCIS), invasive cSCC, and finally metastati...

Keratinocyte Inflammatory Responses

Human Keratinocyte Culture

Stratification of human epidermal cells into multilayered sheets composed of basal and suprabasal layers (resembling the stratum germinativum and stratum spinosum of the epidermis) was studied in a dermal component-free culture system. Although no stratum corneum developed in vitro, this culture system provided a method to study early events in human keratinocyte differentiation. Multiparameter...

Fibrin Stimulates Keratinocyte Proliferation

Received February 9, 2005; revision accepted for publication June 21, 2005. Correspondence: Misa Yamamoto, MT (Medical Technologist), CT (Cytologist), Faculty of Health Sciences, Yamaguchi University School of Medicine, MinamiKogushi 1-1-1, Ube, Yamaguchi, 755-8554, Japan. e-mail: [email protected] Fibrin Stimulates the Proliferation of Human Keratinocytes through the Autocrine Mechani...